Discover the magic of the 3,4-Dihydroquinoxalin-2(1H)-one

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, SDS of cas: 59564-59-9, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 59564-59-9

New Advances in Chemical Research, May 2021. In heterogeneous catalysis, the catalyst is in a different phase from the reactants. SDS of cas: 59564-59-9, We’ll be discussing some of the latest developments in chemical about CAS: 59564-59-9, name is 3,4-Dihydroquinoxalin-2(1H)-one. In an article,Which mentioned a new discovery about 59564-59-9

A new series of 4-acetyl-1-substituted-3,4-dihydroquinoxalin-2(1H)-ones (2?13) were designed and synthesized in order to evaluate their AMPA-receptor antagonism as a potential mode of anticonvulsant activity. The structure of the synthesized compounds was confirmed by elemental analysis and spectral data (IR, 1HNMR, 13CNMR and Mass). The molecular design was performed for all the synthesized compounds to predict their binding affinity to AMPA-receptor in order to rationalize their anticonvulsant activity in a qualitative way. The data obtained from the molecular modeling was strongly correlated with that obtained from the biological screening which revealed that; compounds 12b, 13, 12a and 7a showed the highest binding affinities toward AMPA-receptor and also showed the highest anticonvulsant activities against pentylenetetrazole -induced seizures in experimental mice. The relative potencies of these compounds were 1.66, 1.66, 1.61 and 0.82 respectively, in comparing to diazepam.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, SDS of cas: 59564-59-9, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 59564-59-9

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N161 | ChemSpider