New Advances in Chemical Research, May 2021. In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Reference of 18514-76-6, We’ll be discussing some of the latest developments in chemical about CAS: 18514-76-6, name is 5-Nitroquinoxaline. In an article,Which mentioned a new discovery about 18514-76-6
A series of (3R*,5S*)-omega-substituted-3-carboxy-3,5-dihydroxyalkanoic acids have been synthesized and evaluated as inhibitors of the recombinant human form of ATP-citrate lyase. The best of these have K(i)’s in the 200- 1000 nM range. As the corresponding thermodynamically favored gamma-lactone prodrugs, a number of compounds are able to inhibit cholesterol and fatty acid synthesis in HepG2 cells and reduce plasma triglyceride levels in vivo. The best of these, compound 77, is able to induce clear hypocholesterolemic and hypotriglyceridaemic responses when administered orally to rat and dog. These results provide evidence to support the hypothesis that compounds which inhibit ATP-citrate lyase have the potential to be a novel class of hypolipidemic agent, which possess combined hypocholesterolemic and hypotriglyceridemic activities.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 18514-76-6
Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N852 | ChemSpider