New Advances in Chemical Research, May 2021. The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry.HPLC of Formula: C8H8N2O, In a article, mentioned the application of 59564-59-9, Name is 3,4-Dihydroquinoxalin-2(1H)-one, molecular formula is C8H8N2O
The present study was undertaken to evaluate whether a novel series of 2,6-diaza-5-oxobicyclo[5.4.0]undeca-1(7),8,10-triene derivatives exhibited antagonistic activity for vasopressin V1 and V2 receptors. Most of these compounds were synthesized and showed a high affinity potential for V2 receptor and low to moderate affinity potential for V1 receptor. The most potent and V2-selective compound, N-[4-[2,6-diaza-6-[2-(4- methylpiperazinyl)-2-oxoethyl]-5-oxobicyclo [5.4.0] undeca-1 (7),8,10-trien- 2-yl]-carbonyl]phenyl] [2-(4-methylphenyl)phenyl]formamide (11b), exhibited IC50’s of 2.9 nM for the V2 receptor and 200 nM for the V1 receptor, respectively. When administered orally to rat, 11b showed an approximately 18-fold increased urine volume in comparison with control rat.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, HPLC of Formula: C8H8N2O, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 59564-59-9
Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N177 | ChemSpider