New Advances in Chemical Research, May 2021. The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry.Computed Properties of C8H5N3O2, In a article, mentioned the application of 18514-76-6, Name is 5-Nitroquinoxaline, molecular formula is C8H5N3O2
Rhodium(III)-catalyzed C-H amidation of 2-arylindoles with dioxazolones for the synthesis of indolo[1,2-c]quinazolines is reported. The reaction is compatible with a wide range of electronically diverse 2-arylindoles and dioxazolones, providing indolo[1,2-c]quinazolines in high to excellent yields. Most notably, the combination of this Rh-catalyzed C-H amidation and intramolecular N-H/N-C(O) cyclization enables the most straightforward direct route to indolo[1,2-c]quinazolines to date. Mechanistic studies and evaluation of antitumor activity of these high value heterocycles are disclosed.
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Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N916 | ChemSpider