Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. COA of Formula: C8H4Cl2N2, In a article, mentioned the application of 2213-63-0, Name is 2,3-Dichloroquinoxaline, molecular formula is C8H4Cl2N2
5-Mercapto-3-(4′-pyridyl)-s-triazole (I; R = 4-pyridyl) reacts with alpha-halogenoketones to give 5-aroylmethylthio-3-(4′-pyridyl)-s-triazoles (IIa-f) which on treatment with PPA undergo cyclodehydration to furnish 5-aryl-3-(4′-pyridyl)thiazolo<2,3-c>-s-triazoles (IIIa-f) and not the isomeric 5-aryl-2-(4′-pyridyl)thiazolo<3,2-b>-s-triazoles (VIIIa-f).The structural assignments of III are based on elemental analyses, spectral data and the unequivocal synthesis of IIIa (R = 4-pyridyl; R1 = p-ClC6H4) by POCl3 cyclization of 4-(p-chlorophenyl)-2-isonicotinylhydrazinothiazole (V) obtained from isonicotinyl thiosemicarbazide (IV) and p-chlorophenacyl bromide.A similar condensation of I (R = 4-pyridyl) with 1,2-dibromoethane yields 5,6-dihydro-3-(4′-pyridyl)thiazolo<2,3-c>-s-triazole (VI) and not its isomer, 5,6-dihydro-2-(4′-pyridyl)thiazolo<3,2-b>-s-triazole (IX).This has also been proved by the unequivocal synthesis of VI by the reaction of IV with 1,2-dibromoethane.The reaction of I (R = 4-pyridyl) with 2,3-dichloroquinoxaline gives 3-(4′-pyridyl)-s-triazolo<3',4':2,3>thiazolo<4,5-b>quinoxaline (VII).
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 2213-63-0, and how the biochemistry of the body works.COA of Formula: C8H4Cl2N2
Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1376 | ChemSpider