The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (R)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine( cas:221012-82-4 ) is researched.Recommanded Product: (R)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine.Zhou, Hai-Feng; Fan, Qing-Hua; Tang, Wei-Jun; Xu, Li-Jin; He, Yan-Mei; Deng, Guo-Jun; Zhao, Li-Wen; Gu, Lian-Quan; Chan, Albert S. C. published the article 《Polyethylene glycol as an environmentally friendly and recyclable reaction medium for enantioselective hydrogenation》 about this compound( cas:221012-82-4 ) in Advanced Synthesis & Catalysis. Keywords: polyethylene glycol solvent stereoselective catalytic hydrogenation. Let’s learn more about this compound (cas:221012-82-4).
Polyethylene glycol (PEG) was found to be an inexpensive, non-toxic and recyclable reaction medium for ruthenium- and rhodium-catalyzed asym. hydrogenation of 2-arylacrylic acids (Ru-catalyzed C=C bond reduction), enamides (Rh-catalyzed C=C bond reduction), β-keto esters and simple aromatic ketones (Ru-catalyzed C=O bond reduction). In all cases, high catalytic activities and enantioselectivities have been achieved, which are comparable to those obtained in conventional organic solvent systems. The Ru and Rh catalysts prepared with com. available chiral diphosphine ligands could be readily recycled by simple extraction, as in the case of ionic liquids, and reused up to nine times without obvious loss of catalytic activity and enantioselectivity. The reduced products were obtained from the extracts in high isolated yields. These results indicate that PEGs as new reaction media are attractive alternatives to room temperature ionic liquids
From this literature《Polyethylene glycol as an environmentally friendly and recyclable reaction medium for enantioselective hydrogenation》,we know some information about this compound(221012-82-4)Recommanded Product: (R)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine, but this is not all information, there are many literatures related to this compound(221012-82-4).
Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider