Awesome and Easy Science Experiments about 57825-30-6

Here is a brief introduction to this compound(57825-30-6)Electric Literature of C9H11Br, if you want to know about other compounds related to this compound(57825-30-6), you can read my other articles.

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Discovery of Ipragliflozin (ASP1941): A novel C-glucoside with benzothiophene structure as a potent and selective sodium glucose co-transporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes mellitus, published in 2012-05-15, which mentions a compound: 57825-30-6, mainly applied to Ipragliflozin ASP1941 aryl glucoside benzothiophene preparation antidiabeteic SGLT2 mellitus, Electric Literature of C9H11Br.

A series of C-glucosides with various heteroaromatics has been synthesized and its inhibitory activity toward SGLTs was evaluated. Upon screening several compounds, the benzothiophene derivative I (R =H) was found to have potent inhibitory activity against SGLT2 and good selectivity vs. SGLT1. Through further optimization of 14a, a novel benzothiophene derivative I (R = F) (ipragliflozin, ASP1941) was discovered as a highly potent and selective SGLT2 inhibitor that reduced blood glucose levels in a dose-dependent manner in diabetic models KK-Ay mice and STZ rats.

Here is a brief introduction to this compound(57825-30-6)Electric Literature of C9H11Br, if you want to know about other compounds related to this compound(57825-30-6), you can read my other articles.

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider