Synthetic Route of C7H5ClN4. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 4-Chloro-6-(1H-imidazol-1-yl)pyrimidine, is researched, Molecular C7H5ClN4, CAS is 114834-02-5, about Selective mono-amination of dichlorodiazines. Author is Sengmany, Stephane; Lebre, Julie; Le Gall, Erwan; Leonel, Eric.
3,6-Dichloropyridazine, 4,6-dichloropyrimidine, 2,4-dichloropyrimidine, and 3,5-dichloropyridazine underwent chemoselective monosubstitution reactions with amines using triethylamine as a base in ethanol at either ambient temperature or reflux to give monoamino monochloro pyridazines and pyrimidines. The methodol. is general and efficient despite noticeable differences in reactivity between diazines; while dichloropyridazine and dichloropyrazine require several hours of heating at reflux for the reaction to proceed, dichloropyrimidines reach completion within minutes at room temperature
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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider