The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (R)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine( cas:221012-82-4 ) is researched.SDS of cas: 221012-82-4.Fujimoto, Hayato; Kusano, Momoka; Kodama, Takuya; Tobisu, Mamoru published the article 《Cyclization of Bisphosphines to Phosphacycles via the Cleavage of Two Carbon-Phosphorus Bonds by Nickel Catalysis》 about this compound( cas:221012-82-4 ) in Organic Letters. Keywords: nickel catalyzed cyclization bisphosphine derivative; phosphanickelacycle naphtho preparation crystal structure; mol structure phosphanickelacycle naphtho; phosphacycle preparation. Let’s learn more about this compound (cas:221012-82-4).
The Ni-catalyzed cyclization of bisphosphine derivatives to form various phosphacycles is reported. The reaction proceeds via the cleavage of two C-P bonds of the bisphosphine. Unlike the previously reported Pd catalysts, the use of Ni as a catalyst allows for the cyclization that requires C(alkyl)-P bond cleavage. A phospha-nickelacycle intermediate was successfully isolated and characterized by x-ray crystallog.
There is still a lot of research devoted to this compound(SMILES：COC(C=C1P(C2=CC=CC=C2)C3=CC=CC=C3)=NC(OC)=C1C4=C(OC)N=C(OC)C=C4P(C5=CC=CC=C5)C6=CC=CC=C6)SDS of cas: 221012-82-4, and with the development of science, more effects of this compound(221012-82-4) can be discovered.
Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider