Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 57825-30-6, is researched, Molecular C9H11Br, about Suzuki coupling based synthesis and in vitro cytotoxic evaluation of Fingolimod and analogues, the main research direction is Suzuki coupling synthesis in vitro cytotoxicity Fingolimod analog.Related Products of 57825-30-6.
A concise synthesis of Fingolimod (FTY720) and its analogs was described. The key step involved Suzuki coupling of aryl boronate 11 with different bromides. In addition, the newly synthesized Fingolimod analogs were evaluated for their in vitro cytotoxicity against SMCC-7721 and HL-60 cell lines. The preliminary SAR was discussed.
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Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider