So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Yang, Kai; Qiu, Yatao; Li, Zheng; Wang, Zhaoyang; Jiang, Sheng researched the compound: 8-Hydroxyquinoline 1-oxide( cas:1127-45-3 ).Name: 8-Hydroxyquinoline 1-oxide.They published the article 《Ligands for Copper-Catalyzed C-N Bond Forming Reactions with 1 Mol% CuBr as Catalyst》 about this compound( cas:1127-45-3 ) in Journal of Organic Chemistry. Keywords: aryl halide amine hydroxyquinoline oxide copper Ullman coupling; arylamine preparation; Ullman coupling catalyst hydroxyquinolinoxide copper. We’ll tell you more about this compound (cas:1127-45-3).
Several new ligands were designed to promote copper-catalyzed Ullman C-N coupling reactions. In this group, 8-hydroxyquinoline-N-oxide was found to serve as a superior ligand for CuBr-catalyzed coupling reactions of aryl iodides, bromides, and chlorides with aliphatic amines and N-heterocycles under a low catalyst loading (1% [Cu] mol). Reactions with the inexpensive catalytic system display a high functional group tolerance as well as excellent chemoselectivity.
Here is a brief introduction to this compound(1127-45-3)Name: 8-Hydroxyquinoline 1-oxide, if you want to know about other compounds related to this compound(1127-45-3), you can read my other articles.
Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider