Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 19777-66-3, is researched, Molecular C3H12Cl2N2, about Optically active derivatives of imidazolines. α-Adrenergic blocking properties, the main research direction is imidazoline stereoisomer preparation adrenergic blocker.SDS of cas: 19777-66-3.
The title compounds I (R and R1 = H, Me, or PhCH2; R2 = 1-naphthylmethyl, PhCH2, or 2,6-dichloroaniline) as salts were prepared from an optically active 1,2-diamine-2HCl and an imino ester HCl, and converted to a stable solid salt. I were evaluated for α-adrenergic activity on rabbit aortic strips. Compared to naphazoline or tolazoline, substitution of a Me or PhCH2 at the 4 position of the imidazoline ring resulted in moderate α-blocking activity with no apparent stereoselectivity with such substitution.
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Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider