The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 1-(Bromomethyl)-4-ethylbenzene( cas:57825-30-6 ) is researched.Safety of 1-(Bromomethyl)-4-ethylbenzene.Chai, Xiaoyun; Zhang, Jun; Yu, Shichong; Hu, Honggang; Zou, Yan; Zhao, Qingjie; Dan, Zhigang; Zhang, Dazhi; Wu, Qiuye published the article 《Design, synthesis, and biological evaluation of novel 1-(1H-1,2,4-triazole-1-yl)-2-(2,4-difluorophenyl)-3-substituted benzylamino-2-propanols》 about this compound( cas:57825-30-6 ) in Bioorganic & Medicinal Chemistry Letters. Keywords: triazolyl difluorophenyl aralkylamino propanol preparation antifungal activity computational chem. Let’s learn more about this compound (cas:57825-30-6).
Based on the results of computational docking to the active site of the cytochrome P 450 14α-demethylase (CYP51), a series of 1-(1H-1,2,4-triazole-1-yl)-2-(2,4-difluorophenyl)-3-substituted benzylamino-2-propanols, e.g., I, as analogs of fluconazole were designed, synthesized, and evaluated as antifungal agents. Results of preliminary antifungal tests against eight human pathogenic fungi in vitro showed that all the title compounds exhibited excellent activities with broad spectrum.
There are many compounds similar to this compound(57825-30-6)Safety of 1-(Bromomethyl)-4-ethylbenzene. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.
Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider