Extracurricular laboratory: Synthetic route of 19777-66-3

In addition to the literature in the link below, there is a lot of literature about this compound((S)-Propane-1,2-diamine dihydrochloride)Formula: C3H12Cl2N2, illustrating the importance and wide applicability of this compound(19777-66-3).

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Journal of Organic Chemistry called Synthesis of Optically Active Imidazolines, Azapenams, Dioxocyclams, and Bis-dioxocyclams, Author is Hsiao, Yi; Hegedus, Louis S., which mentions a compound: 19777-66-3, SMILESS is C[C@H](N)CN.[H]Cl.[H]Cl, Molecular C3H12Cl2N2, Formula: C3H12Cl2N2.

Optically active 4-methyl-4-carbomethoxy-Δ2-imidazoline I was efficiently synthesized on a multigram scale. Photolysis of I with (methoxymethylcarbene)chromium complex produced the optically active azapenam II in good yield and with high stereoselectivity. Acid-catalyzed dimerization of II, followed by reduction, produced the optically active dioxocyclam III in good yield. Using a bis-carbene complex, the optically active bis-dioxocyclam IV was produced in excellent yield.

In addition to the literature in the link below, there is a lot of literature about this compound((S)-Propane-1,2-diamine dihydrochloride)Formula: C3H12Cl2N2, illustrating the importance and wide applicability of this compound(19777-66-3).

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider