So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Hasell, T.; Little, M. A.; Chong, S. Y.; Schmidtmann, M.; Briggs, M. E.; Santolini, V.; Jelfs, K. E.; Cooper, A. I. researched the compound: (S)-Propane-1,2-diamine dihydrochloride( cas:19777-66-3 ).Synthetic Route of C3H12Cl2N2.They published the article 《Chirality as a tool for function in porous organic cages》 about this compound( cas:19777-66-3 ) in Nanoscale. Keywords: organic cage compound diastereoselective preparation crystal structure chiral recognition. We’ll tell you more about this compound (cas:19777-66-3).
The investigation of chiral analogs of cages that were previously studied as racemates was described. It was shown that chiral cages could be produced directly from chiral precursors or by separating racemic cages by co-crystallization with a second chiral cage, opening up a route to producing chiral cages from achiral precursors. These chiral cages can be cocrystd. in a modular, ‘isoreticular’ fashion, thus modifying porosity, although some chiral pairings required a specific solvent to direct the crystal into the desired packing mode. Certain cages were shown to interconvert chirality in solution, and the steric factors governing this behavior were explored both by experiment and by computational modeling.
This literature about this compound(19777-66-3)Synthetic Route of C3H12Cl2N2has given us a lot of inspiration, and I hope that the research on this compound((S)-Propane-1,2-diamine dihydrochloride) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider