New downstream synthetic route of 221012-82-4

Compounds in my other articles are similar to this one((R)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine)Product Details of 221012-82-4, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Product Details of 221012-82-4. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: (R)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine, is researched, Molecular C38H34N2O4P2, CAS is 221012-82-4, about Nickel-catalyzed asymmetric α-arylation of ketone enolates. Author is Chen, Guoshu; Kwong, Fuk Yee; Chan, Hoi On; Yu, Wing-Yiu; Chan, Albert S. C..

An atropisomeric dipyridyldiphosphine, P-Phos, can effect highly enantioselective Ni-catalyzed α-arylation of ketone enolates, generated in situ from 1-benzoalkanones, such as 2-methyl-1-tetralone, 2-methyl-1-indanone or 2-methylbenzosuberone, with aryl halides RX (R = Ph, X = Cl, Br, iodo; R = 4-NCC6H4, 4-F3CC6H4, 4-Me3CC6H4, etc., X = Br) to install an all-carbon quaternary stereogenic center in up to 98% ee and excellent yields.

Compounds in my other articles are similar to this one((R)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine)Product Details of 221012-82-4, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider