The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 8-Hydroxyquinoline 1-oxide( cas:1127-45-3 ) is researched.Synthetic Route of C9H7NO2.Larionov, Oleg V.; Stephens, David; Mfuh, Adelphe M.; Arman, Hadi D.; Naumova, Anastasia S.; Chavez, Gabriel; Skenderi, Behije published the article 《Insights into the mechanistic and synthetic aspects of the Mo/P-catalyzed oxidation of N-heterocycles》 about this compound( cas:1127-45-3 ) in Organic & Biomolecular Chemistry. Keywords: oxidation nitrogen heterocycle phosphomolybdic acid catalyst; nitrogen heterocycle oxide preparation. Let’s learn more about this compound (cas:1127-45-3).
A Mo/P catalytic system for an efficient gram-scale oxidation of a variety of nitrogen heterocycles to N-oxides with hydrogen peroxide as terminal oxidant has been investigated. Combined spectroscopic and crystallog. studies point to the tetranuclear Mo4P peroxo complex as one of the active catalytic species present in the solution Based on this finding an optimized catalytic system has been developed. The utility and chemoselectivity of the catalytic system has been demonstrated by the synthesis of over 20 heterocyclic N-oxides.
Although many compounds look similar to this compound(1127-45-3)Synthetic Route of C9H7NO2, numerous studies have shown that this compound(SMILES:OC1=CC=CC2=CC=C[N+]([O-])=C12), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider