The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (R)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine( cas:221012-82-4 ) is researched.Electric Literature of C38H34N2O4P2.Menard, Frederic; Perez, David; Sustac Roman, Daniela; Chapman, Timothy M.; Lautens, Mark published the article 《Ligand-Controlled Selectivity in the Desymmetrization of meso Cyclopenten-1,4-diols via Rhodium(I)-Catalyzed Addition of Arylboronic Acids》 about this compound( cas:221012-82-4 ) in Journal of Organic Chemistry. Keywords: meso cyclopentene dicarbonate boronic acid rhodium catalyst allylic substitution; arylcyclopentenol chiral ligand controlled regioselective stereoselective preparation. Let’s learn more about this compound (cas:221012-82-4).
A highly enantioselective desymmetrization of meso cyclopent-2-ene-1,4-diethyl dicarbonates has been developed using a Rh-catalyzed asym. allylic substitution. Depending on the type of ligand used, each of two regioisomeric products can be obtained in good yield and excellent enantioselectivity. Under rhodium(I) catalysis, bisphosphine P-Phos ligands form trans-1,2-arylcyclopentenols as the major product, whereas Segphos ligands lead predominantly to trans-1,4-arylcyclopentenols.
Although many compounds look similar to this compound(221012-82-4)Electric Literature of C38H34N2O4P2, numerous studies have shown that this compound(SMILES:COC(C=C1P(C2=CC=CC=C2)C3=CC=CC=C3)=NC(OC)=C1C4=C(OC)N=C(OC)C=C4P(C5=CC=CC=C5)C6=CC=CC=C6), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider