New learning discoveries about 13940-83-5

In some applications, this compound(13940-83-5)Safety of Nickel(ii)fluoridetetrahydrate is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Chang, Qing; Luo, Zeshunji; Fu, Licai; Zhu, Jiajun; Yang, Wulin; Li, Deyi; Zhou, Lingping researched the compound: Nickel(ii)fluoridetetrahydrate( cas:13940-83-5 ).Safety of Nickel(ii)fluoridetetrahydrate.They published the article 《A new cathode material of NiF2 for thermal batteries with high specific power》 about this compound( cas:13940-83-5 ) in Electrochimica Acta. Keywords: cathode nickel fluoride thermal battery. We’ll tell you more about this compound (cas:13940-83-5).

Transition metal halides, especially fluorides, are promising candidates used as cathode materials for primary batteries, thanks to their attractive electrochem. properties such as high conversion potential as well as extraordinary specific capacity. The intrinsic thermal stability stemming from the characteristic ionic bond, M-F, also enables them to be applied in some severe conditions. Herein, the authors study the discharge performance of NiF2 under large c.d. (0.1 A cm-2, 0.2 A cm-2 and 0.5 A cm-2), together with extremely high temperature of 520°, 550° and 580°. It can exhibit excellent electrochem. properties with the maximum specific power up to 16.2 kW kg-1 at c.d. of 0.5 A cm-2 and temperature of 550°, at cutoff voltage of 2 V (80% of the peak voltage). When the c.d. is controlled at 0.1 A cm-2, the specific power can also reach at 3.5 kW kg-1 with other parameters as the same. Afterwards, XRD and XPS are conducted to further evidence the discharge mechanism of this process, confirming it as NiF2 + 2Li → Ni + 2LiF. Based on them, probably this work will afford insights into alternatives of cathode materials in the area of high specific power thermal batteries.

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In some applications, this compound(221012-82-4)Computed Properties of C38H34N2O4P2 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Li, Zhanyu; Zhang, Mengru; Zhang, Yu; Liu, Shuang; Zhao, Jinbo; Zhang, Qian published the article 《Multicomponent Cyclopropane Synthesis Enabled by Cu-Catalyzed Cyclopropene Carbometalation with Organoboron Reagent: Enantioselective Modular Access to Polysubstituted 2-Arylcyclopropylamines》. Keywords: enantioselective multicomponent synthesis arylcyclopropylamine; copper catalyzed cyclopropene carbometalation organoboron reagent.They researched the compound: (R)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine( cas:221012-82-4 ).Computed Properties of C38H34N2O4P2. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:221012-82-4) here.

The use of functional-group-tolerant organoboron in lieu of basic organometallic reagents in base-metal-catalyzed cyclopropene carbometalation opens three-component cyclopropane synthesis, as exemplified by the modular assembly of the highly medicinally relevant 2-arylcyclopropylamine (ACPA) framework via stereoselective carboamination. The highly enantioselective version has been realized to afford enantioenriched ACPAs with up to all three cyclopropyl carbons as stereogenic centers in one operation, representing the first example of enantioselective multicomponent cyclopropane synthesis. The reaction significantly improves the efficiency of ACPA synthesis and may inspire the development of other multicomponent cyclopropane syntheses beyond amination.

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In some applications, this compound(1127-45-3)Application In Synthesis of 8-Hydroxyquinoline 1-oxide is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Application In Synthesis of 8-Hydroxyquinoline 1-oxide. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: 8-Hydroxyquinoline 1-oxide, is researched, Molecular C9H7NO2, CAS is 1127-45-3, about Intramolecular hydrogen bonding in 8-quinolinol N-oxides, quinaldinic acid N-oxides and quinoline-2-carboxyamide N-oxide. Deuterium isotope effects on 13C chemical shifts. Author is Dziembowska, Teresa; Rozwadowski, Zbigniew; Hansen, Poul Erik.

Secondary isotope effects on 13C chem. shifts have been measured in a series quinolinols, quinaldinic acid N-oxides and quinoline-2-carboxyamide N-oxide. For 8-quinolinol N-oxides a good correlation was found between δOH and nΔC(OD) isotope effects. The OH and 13C chem. shifts and nΔC(OD) show very small temperature dependences. The primary isotope effects are small, pos. and temperature insensitive. Furthermore, they increase with increasing nΔC(OD). All features point towards a localized hydrogen bond in an asym. double well potential. The quinaldinic acid N-oxides show long-range isotope effects on 13C chem. shifts of both signs with 2ΔC=O(OD) rather small. The primary isotope effects of the quinaldinic acid N-oxide is of order of 0.5 ppm, whereas for its 4-ethoxy-derivative is smaller, ∼0.3 ppm. The OH chem. shifts resonate at the low field ∼18-20 ppm and the OH resonance is fairly broad at room temperature, especially for the 4-ethoxy-derivative The temperature effects on the chem. shifts, primary and secondary isotope effects are small. For quinaldinic acid N-oxides the asym. broad quasi-single potential is suggested.For quinoline-2-carboxyamide N-oxide the isotope effects are small, indicating rather weak hydrogen bond.

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In some applications, this compound(1127-45-3)Recommanded Product: 8-Hydroxyquinoline 1-oxide is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Low-dimensional compounds containing bioactive ligands. Part XVI: Halogenated derivatives of 8-quinolinol N-oxides and their copper(II) complexes》. Authors are Lukoova, Andrea; Baran, Peter; Volarevic, Vladislav; Ilic, Aleksandar; Vilkova, Maria; Litecka, Miroslava; Harmosova, Michaela; Potocnak, Ivan.The article about the compound:8-Hydroxyquinoline 1-oxidecas:1127-45-3,SMILESS:OC1=CC=CC2=CC=C[N+]([O-])=C12).Recommanded Product: 8-Hydroxyquinoline 1-oxide. Through the article, more information about this compound (cas:1127-45-3) is conveyed.

Four N-oxides, 8-quinolinol N-oxide (8-HQNO), 5,7-dichloro-8-quinolinol N-oxide (HdClQNO), 5,7-dibromo-8-quinolinol N-oxide (HdBrQNO) and 7-iodo-8-quinolinol N-oxide (HIQNO) as well as their six copper complexes, CuCl2(8-HQNO)2(H2O) (1), CuCl2(HdClQNO)2(H2O)2 (2), Cu(dClQNO)2(CHCl3) (3), Cu(dClQNO)2(H2O) (4), {[Cu(dBrQNO)2]•2H2O}n (5) and CuCl2(HIQNO)2(H2O)4 (6) were synthesized as possible anticancer agents. Crystal structures of N-oxides contain planar mols. held together via hydrogen bonds involving oxygen atoms of N-oxide groups as acceptors. Crystal structure of 5 represents the first structure of a copper(II) complex with an N-oxide ligand derived from 8-HQNO and is formed by infinite chains. In the chain, the Cu(II) atom coordinates to six oxygen atoms from two bidentate chelating dBrQNO ligands occupying apexes of elongated tetragonal bipyramid with bridging oxygen atoms of N-oxide groups in axial positions. Antiproliferative activity of prepared N-oxides as well as their complexes was studied using in vitro MTT assay against the MDA-MB-231, HCT-116 and A549 cancer cell lines and their selectivity was verified on MSCs cells. Among the tested cancer cell lines, A549 and MDA-MB-231 cells were the most sensitive to the tested complexes. Complex 1 showed the highest cytotoxicity against both tumor cell lines. At concentration, which could be tested in animal models, 1 induced cell death in >50% of cancer cells and in 20% of MSCs indicating its selectivity.

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Interesting scientific research on 57825-30-6

In some applications, this compound(57825-30-6)Safety of 1-(Bromomethyl)-4-ethylbenzene is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Tetrahedron called Construction of polyaromatics via photocyclization of 2-(fur-3-yl)ethenylarenes, using a 3-furyl group as an isopropenyl equivalent synthon, Author is Chen, Ying-Zhe; Ni, Ching-Wen; Teng, Fu-Lin; Ding, Yi-Shun; Lee, Tunng-Hsien; Ho, Jinn-Hsuan, which mentions a compound: 57825-30-6, SMILESS is CCC1=CC=C(CBr)C=C1, Molecular C9H11Br, Safety of 1-(Bromomethyl)-4-ethylbenzene.

The construction of different types of substituted arenes was demonstrated through the photocyclization of 2-(fur-3-yl)ethenylarenes using a 3-furyl group as an isopropenyl equivalent synthon in the photocyclization reaction. The furan portion of the photocyclization intermediate could be fragmented via a base-induced elimination reaction to yield a series of substituted polyaromatics, including naphthalene, benzofuran, benzothiophene, phenanthrene, phenalene, acenaphthene, and triphenylene. Using different reagents, this method made it possible to introduce Me or 2-hydroxyethyl groups as substituents at specific positions in these arenes.

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In some applications, this compound(1127-45-3)COA of Formula: C9H7NO2 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Shrader, William D.; Celebuski, Joseph; Kline, Steven J.; Johnson, David researched the compound: 8-Hydroxyquinoline 1-oxide( cas:1127-45-3 ).COA of Formula: C9H7NO2.They published the article 《Synthesis of a novel hexadentate chelating agent based on 8-hydroxyquinoline》 about this compound( cas:1127-45-3 ) in Tetrahedron Letters. Keywords: hydroxyquinolinecarbonamidoethylamine preparation hexadentate chelating agent; quinolinecarbonamidoethylamine preparation chelating agent; amidation succinimido hydroxyquinolinecarboxylate aminoethylamine. We’ll tell you more about this compound (cas:1127-45-3).

Tris[[(hydroxyquinoline)carbonamido]ethyl]amine (I), a new hexadentate chelator, was prepared by the conversion of 8-hydroxyquinoline to succinimido hydroxyquinolinecarboxylate II and subsequent reaction with N(CH2CH2NH2)3. I is a siderophore analog with a non-naturally occurring binding unit comprising a combination of both O and N donor atoms.

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In some applications, this compound(19777-66-3)Application of 19777-66-3 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Application of 19777-66-3. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: (S)-Propane-1,2-diamine dihydrochloride, is researched, Molecular C3H12Cl2N2, CAS is 19777-66-3, about Resolution of propandiamine and synthesis of dexrazoxane. Author is Wang, Yuling; Song, Hongrui; Song, Aihua.

The resolution of propandiamine and synthesis of dexrazoxane were studied. Using 1,2-propandiamine as primary material, the synthetic method of dexrazoxane by resolution, alkylation and cyclization was established. The L-tartaric acid was used as a resolving reagent, 1,2-propandiamine was resolved and the (+)-enantiomer was obtained. The method of changing 1,2-propandiamine bitartrate into hydrochloride was improved. The method was simpler and might be of application.

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Research on new synthetic routes about 57825-30-6

In some applications, this compound(57825-30-6)COA of Formula: C9H11Br is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-(Bromomethyl)-4-ethylbenzene(SMILESS: CCC1=CC=C(CBr)C=C1,cas:57825-30-6) is researched.Application In Synthesis of 5,5′-Dimethyl-2,2′-bipyridine. The article 《Substituent effects on benzylic radical hydrogen hyperfine coupling constants. Part 4. The effect of branching of the alkyl substituent》 in relation to this compound, is published in Canadian Journal of Chemistry. Let’s take a look at the latest research on this compound (cas:57825-30-6).

The substituent effects on the title hfc constants of m- (I) or p-R1C6H4R2• (II; R = H, Me) are discussed and the ESR of II (R = H, Me; R1 = Me, Et, Me2CH, Me3C) are analyzed. ESR and INDO calculations show that hyperconjugation involving the C-C bond is 40-60% as effective as C-H hyperconjugation for delocalizing spin d. 13C NMR of p-R1C6H4C+Me2 shows that C-C hyperconjugation is 75-90% as effective as C-H hyperconjugation for delocalizing charge d. The inductive effect on the hfc were deted. by the LFER with σm for I; the inductive withdrawal of electron d. leads to a decrease in spin delocalization.

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In some applications, this compound(221012-82-4)Product Details of 221012-82-4 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Lam, Kim-Hung; Chui, Chung-Hin; Gambari, Roberto; Wong, Raymond Siu-Ming; Cheng, Gregory Yin-Ming; Lau, Fung-Yi; Lai, Paul Bo-San; Tong, See-Wai; Chan, Kit-Wah; Wong, Wai-Yeung; Chan, Albert Sun-Chi; Tang, Johnny Cheuk-On published the article 《The preparation of bi-functional organophosphine oxides as potential antitumor agents》. Keywords: BINAP P Phos organophosphine oxide preparation potential antitumor agent.They researched the compound: (R)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine( cas:221012-82-4 ).Product Details of 221012-82-4. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:221012-82-4) here.

Following previously reported pyridinyl phosphine oxides as antitumor agents, the com. available C2-axial chiral organophosphine ligand catalysts, such as 2,2′-bis(diphenylphosphino)-1,1′-binaphthyl (BINAP) 1 and 2,2′,6,6′-tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine (P-Phos) 2 as a convenient source for producing organophosphine oxides were targeted as antitumor leads. Their corresponding chiral and racemic bi-phosphine oxides 3 and 4 can be obtained easily through a simple oxidation step with hydrogen peroxide, and their antitumor activities towards human hepatocellular carcinoma Hep3B cell line were reported. It was found that compound 3 shows stronger antitumor activity than that of 4, where axial chirality cannot improve their activity. Further athymic nude mice Hep3B xenograft model demonstrates the attractive in vivo antitumor potential of 3.

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In some applications, this compound(57825-30-6)Name: 1-(Bromomethyl)-4-ethylbenzene is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Name: 1-(Bromomethyl)-4-ethylbenzene. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 1-(Bromomethyl)-4-ethylbenzene, is researched, Molecular C9H11Br, CAS is 57825-30-6, about Structurally Simple Inhibitors of Lanosterol 14α-Demethylase Are Efficacious In a Rodent Model of Acute Chagas Disease. Author is Suryadevara, Praveen Kumar; Olepu, Srinivas; Lockman, Jeffrey W.; Ohkanda, Junko; Karimi, Mandana; Verlinde, Christophe L. M. J.; Kraus, James M.; Schoepe, Jan; Van Voorhis, Wesley C.; Hamilton, Andrew D.; Buckner, Frederick S.; Gelb, Michael H..

We report structure-activity studies of a large number of dialkyl imidazoles as inhibitors of Trypanosoma cruzi lanosterol-14α-demethylase (L14DM). The compounds have a simple structure compared to posaconazole, another L14DM inhibitor that is an anti-Chagas drug candidate. Several compounds display potency for killing T. cruzi amastigotes in vitro with values of EC50 in the 0.4-10 nM range. Two compounds were selected for efficacy studies in a mouse model of acute Chagas disease. At oral doses of 20-50 mg/kg given after establishment of parasite infection, the compounds reduced parasitemia in the blood to undetectable levels, and anal. of remaining parasites by PCR revealed a lack of parasites in the majority of animals. These dialkyl imidazoles are substantially less expensive to produce than posaconazole and are appropriate for further development toward an anti-Chagas disease clin. candidate.

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