Khalymbadzha, Igor A’s team published research in Synthesis in 2018-06-30 | 89898-96-4

Synthesis published new progress about C-C bond formation. 89898-96-4 belongs to class quinoxaline, and the molecular formula is C8H5N3O3, COA of Formula: C8H5N3O3.

Khalymbadzha, Igor A.; Fatykhov, Ramil F.; Chupakhin, Oleg N.; Charushin, Valery N.; Tseitler, Tatiana A.; Sharapov, Ainur D.; Inytina, Anna K.; Kartsev, Victor G. published the artcile< Transition-Metal-Free C-C Coupling of 5,7-Dihydroxybenzopyrones with Quinoxalones and Pteridinones>, COA of Formula: C8H5N3O3, the main research area is dihydroxycoumarin quinoxalone regioselective chemoselective nucleophilic substitution oxidation green chem; dihydroxy oxochromenyl quinoxalinone preparation; pteridinone dihydroxycoumarin regioselective chemoselective nucleophilic substitution oxidation green chem; oxochromenyl tetrahydropteridinedione dihydroxy preparation.

A new synthetic protocol for nucleophilic substitution of hydrogen in quinoxalones and pteridinones by the action of 5,7-dihydroxycoumarins and related m-dihydroxybenzene compounds were developed. The C-C coupling reaction proved to proceed smoothly under rather mild conditions, thus giving the corresponding C-H functionalized products in good yields. The advantages of this environmentally benign protocol were high regio- and chemoselectivity and an easy workup procedure. Direct incorporation of the coumarin moiety into the pyrazine ring in pteridines or quinoxalines provided a short pathway to pyrazine-coumarin hybrid compounds

Synthesis published new progress about C-C bond formation. 89898-96-4 belongs to class quinoxaline, and the molecular formula is C8H5N3O3, COA of Formula: C8H5N3O3.

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider