Minisci, Francesco; Citterio, Attilio; Vismara, Elena; Giordano, Claudio published the artcile< Polar effects in free-radical reactions. New synthetic developments in the functionalization of heteroaromatic bases by nucleophilic radicals>, Related Products of 5182-90-1, the main research area is lepidine alc nucleophilic radical substitution; hydroxylaminium salt titanium substitution catalyst; hydroxyalkyllepidine; substitution catalyst benzoyl peroxide hydrogen; carbamoylation quinoline acridine pyrazine benzothiazole; heteroaromatic base carbamoylation peroxide catalyst; dioxane hydrofuran lepidine radical substitution.
Direct substitution of protonated heteroaromatic bases by nucleophilic carbon-centered radicals involved use of the redox system N+H3OH/Ti(III) in several solvents, use of benzoyl peroxide in alcs., and carbamoylation by HCONH2 and H2O2 in the presence of catalytic Fe(II). Thus lepidine I (R = H) in MeOH gave 98% I (R = CH2OH) in the presence of benzoyl peroxide. These systems gave hitherto unobtainable substitution products and reactions of industrial interest. Polar effects determine reactivity, selectivity and synthetic applications; in particular the role of the strongly nucleophilic intermediate radicals of pyridinyl type in the rearomatization step is emphasized.
Tetrahedron published new progress about Carbamoylation. 5182-90-1 belongs to class quinoxaline, and the molecular formula is C9H7N3O, Related Products of 5182-90-1.
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider