Wang, Qing-Qing; Xu, Kun; Jiang, Yang-Ye; Liu, Yong-Guo; Sun, Bao-Guo; Zeng, Cheng-Chu published the artcile< Electrocatalytic Minisci Acylation Reaction of N-Heteroarenes Mediated by NH4I>, HPLC of Formula: 23088-24-6, the main research area is acylpyrazine acylquinoxaline heteroaryl ketone preparation; chemoselective green Minisci acylation pyrazine quinoxaline ketoacid ammonium iodide; ammonium iodide mediator electrochem Minisci acylation pyrazine quinoxaline ketoacid; mechanism electrochem Minisci acylation pyrazine quinoxaline ketoacid.
Electron-deficient aromatic nitrogen heterocycles, particularly pyrazines and quinoxalines, underwent chemoselective and green electrochem. Minisci acylations with α-ketoacids such as pyruvic acid mediated by NH4I, LiClO4, and hexafluoroisopropanol in MeCN to give heteroaryl ketones such as 2-acetylquinoxaline in 18-65% yields. Cyclic voltammetry and control experiments were used to delineate the mechanism of the Minisci acylation; I2 formed in situ likely reacts with carboxylate anions to yield acyl hypoiodites which then undergo decarboxylation to acyl radicals.
Organic Letters published new progress about Acylation, regioselective (Minisci, chemoselective, electrochem.). 23088-24-6 belongs to class quinoxaline, and the molecular formula is C9H5N3, HPLC of Formula: 23088-24-6.
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider