On July 1, 2016, Huang, Wen-Xue; Liu, Lian-Jin; Wu, Bo; Feng, Guang-Shou; Wang, Baomin; Zhou, Yong-Gui published an article.Safety of 5,6,7,8-Tetrahydroquinoxaline The title of the article was Synthesis of Chiral Piperazines via Hydrogenation of Pyrazines Activated by Alkyl Halides. And the article contained the following:
A facile method has been developed for the synthesis of chiral piperazines through Ir-catalyzed hydrogenation of pyrazines activated by alkyl halides, giving a wide range of chiral piperazines including 3-substituted as well as 2,3- and 3,5-disubstituted ones with up to 96% ee. The high enantioselectivity, easy scalability, and concise drug synthesis demonstrate the practical utility. The experimental process involved the reaction of 5,6,7,8-Tetrahydroquinoxaline(cas: 34413-35-9).Safety of 5,6,7,8-Tetrahydroquinoxaline
The Article related to pyrazine alkyl halide iridium chiral ligand hydrogenation catalyst, piperazine stereoselective preparation, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazines and Quinoxalines (Including Piperazines) and other aspects.Safety of 5,6,7,8-Tetrahydroquinoxaline
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider