On March 20, 2008, Kumar, Ajeet; Kumar, Santosh; Saxena, Amit; De, Arnab; Mozumdar, Subho published an article.Formula: C8H10N2 The title of the article was Ni-nanoparticles: An efficient catalyst for the synthesis of quinoxalines. And the article contained the following:
Biol. active quinoxalines were efficiently synthesized in excellent yields and in less reaction time using inexpensive, monodispersed and easily recyclable Ni-nanoparticles. In order to elucidate the role of the Ni-nanoparticles, a control reaction was conducted using glyoxal and o-phenylenediamine in acetonitrile in the absence of Ni-nanoparticles. Quinoxaline was formed in around 10 h with a 30% yield. However, the same reaction carried out in acetonitrile using 10 mol.% of Ni-nanoparticles (14-18 nm) at 25° and stirred under N2 gave quinoxaline in quant. yield in 10 min. The separation of the product was facile and the catalyst could be separated and recycled by mild centrifugation. This method is very quick, avoids the use of expensive reagents, high temperatures (the reaction takes place at room temperature) and leads to excellent yield. The experimental process involved the reaction of 5,6,7,8-Tetrahydroquinoxaline(cas: 34413-35-9).Formula: C8H10N2
The Article related to quinoxaline preparation glyoxal phenylenediamine nickel nanoparticle catalyst, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazines and Quinoxalines (Including Piperazines) and other aspects.Formula: C8H10N2
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider