On May 2, 2003, Skupinska, Krystyna A.; McEachern, Ernest J.; Baird, Ian R.; Skerlj, Renato T.; Bridger, Gary J. published an article.Electric Literature of 34413-35-9 The title of the article was Enzymatic Resolution of Bicyclic 1-Heteroarylamines Using Candida antarctica Lipase B. And the article contained the following:
Candida antarctica lipase B has been used to kinetically resolve a structurally diverse series of bicyclic 1-heteroaryl primary amines, e.g. 8-amino-5,6,7,8-tetrahydroquinoline, 5-amino-5,6,7,8-tetrahydroquinoxaline, etc., by enantioselective acetylation. High yields of either enantiomer could be obtained with excellent enantioselectivity (90-99% ee), while the undesired enantiomer could, in some cases, be recycled by thermal racemization. The absolute stereochem. of the products was confirmed by an X-ray crystallog. The experimental process involved the reaction of 5,6,7,8-Tetrahydroquinoxaline(cas: 34413-35-9).Electric Literature of 34413-35-9
The Article related to amine heteroaryl bicyclic acetylation enzymic resolution lipase, Heterocyclic Compounds (More Than One Hetero Atom): General and other aspects.Electric Literature of 34413-35-9
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider