On April 30, 2002, Adams, T. B.; Doull, J.; Feron, V. J.; Goodman, J. I.; Marnett, L. J.; Munro, I. C.; Newberne, P. M.; Portoghese, P. S.; Smith, R. L.; Waddell, W. J.; Wagner, B. M. published an article.Formula: C8H10N2 The title of the article was The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients. And the article contained the following:
A review. Elements that are fundamental to the safety evaluation of flavor ingredients include exposure, structural analogy, metabolism, pharmacokinetics and toxicol. Flavor ingredients are evaluated individually taking into account the available scientific information on the group of structurally related substances. Scientific data relevant to the safety evaluation of the use of pyrazine derivatives as flavoring ingredients is evaluated. The experimental process involved the reaction of 5,6,7,8-Tetrahydroquinoxaline(cas: 34413-35-9).Formula: C8H10N2
The Article related to review pyrazine flavor gras, Food and Feed Chemistry: Reviews and other aspects.Formula: C8H10N2
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider