Liu, Yunkui published the artcileMultifold Bond Cleavage and Formation between MeOH and Quinoxalines (or Benzothiazoles): Synthesis of Carbaldehyde Dimethyl Acetals, Product Details of C12H8N2S, the main research area is quinoxaline methanol potassium persulfate cross coupling; quinoxalinyl carbaldehyde dimethyl acetal preparation green chem; benzothiazole methanol potassium persulfate cross coupling; benzothiazolyl carbaldehyde dimethyl acetal preparation green chem.
A K2S2O8-mediated direct cross-coupling of quinoxalines (or benzothiazoles) with methanol leading to 2-quinoxalinyl (or 2-benzothiazolyl) carbaldehyde di-Me acetals has been achieved. 2-Quinoxalinyl carbaldehyde di-Me acetals were readily converted into 2-quinoxalinyl carbaldehydes in good to excellent yields under acidic conditions. Preliminary mechanistic studies suggest that the reaction proceeds via multifold bond cleavage and formation between methanol and N-heterocycles involving a dioxygen-participated radical process. This method allows for the synthesis of a variety of 2-quinoxalinyl (or 2-benzothiazolyl) carbaldehyde di-Me acetals directly via cross-coupling of simple N-heterocyclic C-H bond and methanol under aldehyde-, acid-, and transition-metal-free conditions.
Journal of Organic Chemistry published new progress about Aryl aldehydes, heteroaryl Role: SPN (Synthetic Preparation), PREP (Preparation) (quinoxalinyl). 40353-41-1 belongs to class quinoxaline, name is 2-(Thiophen-2-yl)quinoxaline, and the molecular formula is C12H8N2S, Product Details of C12H8N2S.
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider