Laru, Sudip published the artcileRu(II)-Catalyzed Switchable C-H Alkylation and Spirocyclization of 2-Arylquinoxalines with Maleimides via ortho-C-H Activation, Application of 2-(Thiophen-2-yl)quinoxaline, the main research area is arylquinoxaline maleimide ruthenium catalyst regioselective alkylation; quinoxalinylaryl succinimide preparation; maleimide arylquinoxaline ruthenium catalyst regioselective oxidative spirocyclization; spiro indenoquinoxaline pyrrolidinedione preparation.
A Ru(II)-catalyzed facile and controllable protocol for C-H alkylation and spirocyclization of 2-arylquinoxalines with maleimides were achieved under ambient air in high yields. Sequential ortho-C-H activation and C-annulation resulted in the formation of diverse polyheterocycles containing spiro[indeno[1,2-b]quinoxaline-11,3′-pyrrolidine]-2′,5′-diones, which is of potent interest in medicinal chem. Mechanistic investigations suggested a reversible cleavage of the ortho-C-H bond in the turnover-limiting step.
Journal of Organic Chemistry published new progress about Alkylation catalysts, regioselective. 40353-41-1 belongs to class quinoxaline, name is 2-(Thiophen-2-yl)quinoxaline, and the molecular formula is C12H8N2S, Application of 2-(Thiophen-2-yl)quinoxaline.
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider