Sawatzky, Ryan S. published the artcile(DPEPhos)Ni(mesityl)Br: An Air-Stable Pre-Catalyst for Challenging Suzuki-Miyaura Cross-Couplings Leading to Unsymmetrical Biheteroaryls, Application In Synthesis of 40353-41-1, the main research area is heteroaryl halide heteroaryl boronic acid nickel Suzuki Miyaura; preparation unsym biheteroaryl; nickel Suzuki Miyaura cross coupling catalyst.
The successful application of (DPEPhos)Ni(mesityl)Br as a pre-catalyst in the Suzuki-Miyaura cross-coupling of heteroaryl chlorides or bromides and heteroaryl boronic acids is reported. The use of (DPEPhos)Ni(mesityl)Br in this context allows for such reactions to be conducted under mild conditions (2 mol% Ni, 25 °C), including cross-couplings leading to unsym. biheteroaryls. Successful transformations of this type involving problematic pyridinyl boronic acid substrates (10 mol% Ni, 60 °C) are also described.
Synlett published new progress about Aryl halides Role: RCT (Reactant), RACT (Reactant or Reagent). 40353-41-1 belongs to class quinoxaline, name is 2-(Thiophen-2-yl)quinoxaline, and the molecular formula is C12H8N2S, Application In Synthesis of 40353-41-1.
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider