Srinivas, B.’s team published research in Pharma Chemica in 2015 | CAS: 39267-05-5

Pharma Chemica published new progress about Antibacterial agents. 39267-05-5 belongs to class quinoxaline, name is 2,3-Dichloro-6-methylquinoxaline, and the molecular formula is C9H6Cl2N2, Formula: C9H6Cl2N2.

Srinivas, B. published the artcileSynthesis and anti-microbial activity of novel series of Substituted 2-(Tetrazolo[1,5-a]quinoxalin-4-yl)-2,3-dihydrophthalazine-1,4-dione derivatives, Formula: C9H6Cl2N2, the main research area is tetrazoloquinoxalinyl dihydrophthalazine dione preparation antibacterial antifungal.

A novel and efficient synthesis of 2-(substituted tetrazolo[1,5-a]quinoxalin-4-yl)-2,3-dihydrophthalazine-1,4-diones I (R1 = H, CH3, Cl, Br, NO2, OCH3; R2 = H, CH3) has been carried out. The substituted 4-hydrazinyl tetrazoloquinoxalines were treated with phthalic anhydride. All the synthesized compounds were screened for anti-microbial activity. Among all the synthesized compounds I (R1 = R2 = H, CH3) and I (R1 = Cl, Br, NO2, OCH3; R2 = H) showed moderate activity against gram-pos. bacterial strains S. aureus and gram-neg. bacterial strains E. coli. Compound I (R1 = NO2; R2 = H) showed appreciable activity against C. albicans and A. niger fungal strains.

Pharma Chemica published new progress about Antibacterial agents. 39267-05-5 belongs to class quinoxaline, name is 2,3-Dichloro-6-methylquinoxaline, and the molecular formula is C9H6Cl2N2, Formula: C9H6Cl2N2.

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider