Thabit, Mohamed G. published the artcileSynthesis and biological evaluation of new 3-(4-substituted phenyl)aminoquinoxaline derivatives as anticancer agents, Recommanded Product: 2,3-Dichloro-6-methylquinoxaline, the main research area is phenylaminoquinoxaline preparation anticancer mol modeling human.
Quinoxaline derivatives e.g. I, were synthesized and evaluated for their in vitro growth inhibitory activities against liver carcinoma cell line (HEPG2) using the sulforhodiamine B assay. The synthesis was achieved by reaction of 2,3-dichloroquinoxalines with 4-aminoacetophenone to give the corresponding 2-(4-acetylphenylamino)-3-quinoxaline derivatives Claisen-Schmidt condensation reaction of these quinoxaline derivatives with furfuraldehyde gave enones, which were transformed into pyridines, isoxazolines, pyrazolines, and pyrimidines via several synthetic routes. Virtual screening was carried out by mol. modeling evaluation of the designed compounds Biol. evaluation of the prepared compounds showed that most of the synthesized compounds exhibit more than 50% growth inhibitory.
Heterocyclic Communications published new progress about Antitumor agents. 39267-05-5 belongs to class quinoxaline, name is 2,3-Dichloro-6-methylquinoxaline, and the molecular formula is C9H6Cl2N2, Recommanded Product: 2,3-Dichloro-6-methylquinoxaline.
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider