Kocak, Engin published the artcileValidation of spectrophotometric method to quantify varenicline content in tablets, Name: 7,8,9,10-Tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline (2R,3R)-2,3-dihydroxysuccinate, the publication is Asian Journal of Chemistry (2013), 25(4), 1845-1848, database is CAplus.
Varenicline is a nicotinic receptor partial agonist used to treat smoking addiction. The objective of this work was to develop and validate UV-Vis spectrophotometric method for the determination of varenicline in tablets. In this study, 0.01 M phosphate buffer arranged to pH 7 was used to prepare standard stock solutions from varenicline tartrate salt, as well used to dissolve the commercials tablet and synthetic tablet solutions UV-VIS spectrophotometric determination was performed at 319 nm wavelength having no interference coming from matrix components. The developed method was linear within the range 1-100 μg mL-1. Method validation was performed according to the ICH guideline and the results show that this simple and low cost method is precise, accurate, robust and rugged to be proposed for the routine anal. in quality control laboratories
Asian Journal of Chemistry published new progress about 375815-87-5. 375815-87-5 belongs to quinoxaline, auxiliary class Neuronal Signaling,AChR,Natural product, name is 7,8,9,10-Tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline (2R,3R)-2,3-dihydroxysuccinate, and the molecular formula is C17H19N3O6, Name: 7,8,9,10-Tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline (2R,3R)-2,3-dihydroxysuccinate.
Referemce:
https://en.wikipedia.org/wiki/Quinoxaline,
Quinoxaline | C8H6N2 | ChemSpider