Halo o-phenylenediamines and derived heterocyles. Hydrodechlorination of chloroquinoxalines was written by Burton, D. E.;Hughes, D.;Newbold, G. T.;Elvidge, J. A.. And the article was included in Journal of the Chemical Society [Section] C: Organic in 1968.Name: 6-Chloroquinoxaline This article mentions the following:
Treatment of 5,6,8-trichloro-7-methylquinoxaline (I) with alkali in aqueous EtOH gives 5,8-dichloro-6-methylquinoxaline (II) cleanly in good yield. 5,6,7,8-Tetrachloroquinoxaline similarly, though less satisfactorily, yields 5,6,8-trichloroquinoxaline and 5,8-dichloroquinoxaline. Further experiments with a bearing on the course of these reactions are described and a possible mechanism is discussed. The preparation of 5,8-dichloro-6-ethoxy-7-methylquinoxaline, a possible product from the reaction I → II, and unambiguous syntheses of III and 5,7-dichloro-6-methylquinoxaline are described. Ir and 1H N.M.R. data for several quinoxalines and their intermediates are also given. In the experiment, the researchers used many compounds, for example, 6-Chloroquinoxaline (cas: 5448-43-1Name: 6-Chloroquinoxaline).
6-Chloroquinoxaline (cas: 5448-43-1) belongs to quinoxaline derivatives. Compounds possessing quinoxaline derivatives were bestowed with a variety of significant biological properties such as antiviral, antimalarial, anticancer, DNA intercalation, DNA duplex stabilization, and many others. Quinoxaline-1,4-di-N-oxide derivatives have shown to improve the biological results and are endowed with anti-viral, anti-cancer, anti-bacterial, and anti-protozoal activities with application in many other therapeutic areas.Name: 6-Chloroquinoxaline
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider