A Green, Scalable, and Catalyst-Free One-Minute Synthesis of Quinoxalines was written by Elumalai, Vijayaragavan;Hansen, Joern H.. And the article was included in SynOpen in 2021.Safety of 6-Chloroquinoxaline This article mentions the following:
A highly efficient and catalyst-free protocol was reported for the synthesis of quinoxalines via the classical cyclocondensation reaction between aryldiamines and dicarbonyl compounds Remarkably simple and green reaction conditions employed methanol as solvent afforded medium to excellent yield of quinoxalines after only one-minute reaction time at ambient temperature The conditions allow at least 10 g scale synthesis of quinoxalines and preferred starting point for optimization and method of choice for applications in the synthetic community. In the experiment, the researchers used many compounds, for example, 6-Chloroquinoxaline (cas: 5448-43-1Safety of 6-Chloroquinoxaline).
6-Chloroquinoxaline (cas: 5448-43-1) belongs to quinoxaline derivatives. Quinoxalines are important class of heterocyclic compounds, associated with wider pharmacological applications. They are well-known for application in organic light emitting devices, polymers and pharmaceutical agents. The quinoxaline-containing polymers are applicable in optical devices due to their thermal stability and low band gap.Safety of 6-Chloroquinoxaline
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider