1-Alkyl-4-oxo-1,4-dihydropyrido[2,3-b]quinoxaline-3-carboxylic acids with antibacterial action was written by Pesson, Marcel;De Lajudie, Pierre;Antoine, Michel;Chabassier, Simone;Girard, Philippe. And the article was included in Comptes Rendus des Seances de l’Academie des Sciences, Serie C: Sciences Chimiques in 1976.SDS of cas: 49679-45-0 This article mentions the following:
Pyridoquinoxalinecarboxylic acids I (R = H; R1 = Me, Et; R2 = H, Me, Cl, OMe; R3 = H, Me, OMe) were prepared by treating the quinoxalines II (R = Me, Et, R4 = Cl) with R1NHCH2CH2CO2H, esterifying II (R4 = NR1CH2CH2CO2H), cyclizing II (R4 = NR1CH2CH2CO2R), brominating-dehydrobrominating the dihydro derivatives of I (R = Me, Et), and saponifying I (R = Me, Et). I have bactericidal activity, which is reduced by substitution in the 7- or 8-positions. In the experiment, the researchers used many compounds, for example, Ethyl 3-chloroquinoxaline-2-carboxylate (cas: 49679-45-0SDS of cas: 49679-45-0).
Ethyl 3-chloroquinoxaline-2-carboxylate (cas: 49679-45-0) belongs to quinoxaline derivatives. Quinoxaline derivatives are important constituents of pharmacologically active compounds, including antibacterial, antibiotic and antineoplastic, antifungal, anti-inflammatory and analgesic drugs. They are well-known for application in organic light emitting devices, polymers and pharmaceutical agents. The quinoxaline-containing polymers are applicable in optical devices due to their thermal stability and low band gap.SDS of cas: 49679-45-0
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider