4-Pyrones. 42. Preparation and reactions of 3-acetoacetyl-2-ethoxyquinoxaline was written by Eiden, F.;Bachmann, G.. And the article was included in Archiv der Pharmazie (Weinheim, Germany) in 1973.Formula: C11H9ClN2O2 This article mentions the following:
The quinoxaline I (R = COCH2COMe) (II) was prepared in 83% yield by reaction of I (R = CO2Et) with Me2CO-NaH. Reaction of II with N2H4 yielded 92% I (R = 5-methyl-3-pyrazolyl). Reaction of II with o-(H2N)2C6H4 gave 61% I (R = 2-methyl-1,5-benzodiazepin-4-yl). Reaction of II with PhNHNH2 gave 70% I (R = 1- and 2-phenyl-5-methyl-3-pyrazolyl), reaction of II with HONH2 yielded 75% I (R = 5-methyl-3- and 3-methyl-5-isoxazolyl). The single components of these isomeric mixtures were determined by NMR spectra. In the experiment, the researchers used many compounds, for example, Ethyl 3-chloroquinoxaline-2-carboxylate (cas: 49679-45-0Formula: C11H9ClN2O2).
Ethyl 3-chloroquinoxaline-2-carboxylate (cas: 49679-45-0) belongs to quinoxaline derivatives. Quinoxaline is isomeric with other naphthyridines including quinazoline, phthalazine and cinnoline. Quinoxaline and its analogues may also be formed by reduction of amino acids substituted 1,5-difluoro-2,4-dinitrobenzene (DFDNB),One study used 2-iodoxybenzoic acid (IBX) as a catalyst in the reaction of benzil with 1,2-diaminobenzene.Formula: C11H9ClN2O2
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider