Synthesis and reactions of 1H-1,5-benzodiazepino[2,3-b]quinoxaline, a new heterocyclic system was written by Pillai, P. Madhavan;Bhat, V. Sanjeev. And the article was included in Synthetic Communications in 1991.Application of 49679-45-0 This article mentions the following:
Title compounds I (R = H, OH, Cl, OMe, OEt, OCHMe2, NR12; R1 = H, Et; NR12 = morpholino, piperidino, 1-pyrrolidinyl) were prepared by elaboration of I (R = OH) which was prepared in high yields by the cyclocondensation of o-C6H4(NH2)2 with quinoxalinecarboxylates II (R2 = Cl, OH). In the experiment, the researchers used many compounds, for example, Ethyl 3-chloroquinoxaline-2-carboxylate (cas: 49679-45-0Application of 49679-45-0).
Ethyl 3-chloroquinoxaline-2-carboxylate (cas: 49679-45-0) belongs to quinoxaline derivatives. Quinoxalines have received a significant amount of attention due to their potential use in fighting various pathophysiological conditions like epilepsy, Parkinson’s, and Alzheimer’s diseases. The parent substance of the group, quinoxaline, results when glyoxal is condensed with 1,2-diaminobenzene. Substituted derivatives arise when α-ketonic acids, α-chlorketones, α-aldehyde alcohols and α-ketone alcohols are used in place of diketones.Application of 49679-45-0
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider