Synthesis, Photophysical Properties, and Antimicrobial Activity of Novel Styryl Colorants Derived from 7-Methoxy-1,4-diphenethyl-1,2,3,4-tetrahydroquinoxaline-6-carbaldehyde was written by Jarag, K. J.;Jagtap, A. R.;Borse, B. N.;Shukla, S. R.;Shankarling, G. S.. And the article was included in Journal of Heterocyclic Chemistry in 2012.Safety of 6-Methoxyquinoxaline This article mentions the following:
The novel 1,4-diphenethyl-1,2,3,4-tetrahydro-7-methoxyquinoxalin-6-carbaldehyde was synthesized by reductive alkylation of 6-methoxy quinoxaline with Ph acetic acid and was further subjected to Knoevenagel condensation with various active methylene compounds to synthesize novel styryl colorants. Photophys. properties of styryl colorants were studied using UV-visible and fluorescence spectroscopy. These colorants displayed orange to violet hue and showed fluorescence emission maxima in the region of 560-640 nm, and displayed a large Stokes shift (85-104 nm). Compounds were subjected to thermogravimetric anal. which showed excellent stability up to 310°C. These styryl compounds were evaluated for their antimicrobial study as antifungal against Candida albicans C. albicans and Aspergillus niger and antibacterial against Escherichia coli and Staphylococcus aureus. The results revealed good antimicrobial activity against tested organisms. The synthesized chromophores were characterized using elemental anal., FTIR, 13C-NMR and 1H-NMR spectroscopy and mass spectrometry. In the experiment, the researchers used many compounds, for example, 6-Methoxyquinoxaline (cas: 6639-82-3Safety of 6-Methoxyquinoxaline).
6-Methoxyquinoxaline (cas: 6639-82-3) belongs to quinoxaline derivatives. Quinoxalines have received a significant amount of attention due to their potential use in fighting various pathophysiological conditions like epilepsy, Parkinson’s, and Alzheimer’s diseases. Quinoxalines are used as dyes, pharmaceuticals, and antibiotics such as echinomycin, levomycin exhibiting antitumoral properties. Quinoxalines establish also the basis of anthelmintics and receptor antagonists.Safety of 6-Methoxyquinoxaline
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider