Direct C3-H carbamoylation of quinoxalin-2(1H)-ones with isocyanides enabled by selectfluor II under mild conditions was written by Li, Jing;Hu, Jie;Xiao, Yao;Yin, Kun;Dan, Wenyan;Fan, Suhua;Jin, Feng;Wu, Hai;Zhang, Ronghua;Li, Jian. And the article was included in Tetrahedron Letters in 2022.Quality Control of 2-Quinoxalinol This article mentions the following:
A F reagent-mediated direct C-H carbamoylation of quinoxalin-2(1H)-ones had been developed. Under room temperature, a variety of isocyanides were employed to couple well with quinoxalin-2(1H)-ones affording alkyl-oxo-quinoxaline-carboxamide I [R1 = H, Me, Ph, etc.; R2 = t-Bu, Bn, 1-naphthyl, etc.; R3 = H, 7-Ph, 6,7-di-Me, etc.]. This metal-free mild strategy tolerated a wide range of functional groups and shows environmental friendliness and practicality. In the experiment, the researchers used many compounds, for example, 2-Quinoxalinol (cas: 1196-57-2Quality Control of 2-Quinoxalinol).
2-Quinoxalinol (cas: 1196-57-2) belongs to quinoxaline derivatives. Quinoxaline is isomeric with other naphthyridines including quinazoline, phthalazine and cinnoline. They are well-known for application in organic light emitting devices, polymers and pharmaceutical agents. The quinoxaline-containing polymers are applicable in optical devices due to their thermal stability and low band gap.Quality Control of 2-Quinoxalinol
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider