Visible-Light Organophotoredox-Mediated [3 + 2] Cycloaddition of Arylcyclopropylamine with Structurally Diverse Olefins for the Construction of Cyclopentylamines and Spiro[4.n] Skeletons was written by Luo, Zhengshan;Cao, Bowen;Song, Tianhang;Xing, Zequn;Ren, Jun;Wang, Zhongwen. And the article was included in Journal of Organic Chemistry in 2022.Computed Properties of C8H4Cl2N2 This article mentions the following:
A visible-light-mediated [3 + 2] cycloaddition of arylcyclopropylamine with structurally diverse olefins was developed using QXPT-NPh I as a highly efficient organic photoredox catalyst. The use of various alkyl-substituted alkenes in intermol. [3 + 2] cycloadditions with cyclopropylamine was first achieved. A general and efficient strategy for the construction of compounds containing structurally diverse cyclopentane-based spiro[4.n] skeletons such as II with 1,3-difunctional groups was also developed, which broadly exist in natural products and synthetic mols. Furthermore, a hydrogen-bond mode between the arylcyclopropylamine and the photocatalyst QXPT-NPh was proposed. In the experiment, the researchers used many compounds, for example, 2,3-Dichloroquinoxaline (cas: 2213-63-0Computed Properties of C8H4Cl2N2).
2,3-Dichloroquinoxaline (cas: 2213-63-0) belongs to quinoxaline derivatives. Condensed heterocycles of quinoxalines have become attractive targets in synthetic and medicinal chemistry due to their significant biological activities. The antitumoral properties of quinoxaline compounds have been of interest. Recently, quinoxaline and its analogs have been investigated as the catalyst’s ligands.Computed Properties of C8H4Cl2N2
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider