Copper catalyzed aerobic oxidative amination of 3,4-dihydroquinoxalin-2(1H)-ones was written by Wan, Shuocheng;Wang, Jie;Huo, Congde. And the article was included in Tetrahedron Letters in 2021.Recommanded Product: 2-Quinoxalinol This article mentions the following:
A copper catalyzed aerobic sp3 C-H amination of 3,4-dihydroquinoxalin-2(1H)-ones is developed. This protocol provides a concise method to access 3-aminoquinoxalinone derivatives with good functional-group tolerances, utilizing primary and secondary aliphatic amines as nitrogen sources under mild and simple reaction conditions. It provides a practical approach to the synthesis of pharmaceutical active 3-aminoquinoxalinones. In the experiment, the researchers used many compounds, for example, 2-Quinoxalinol (cas: 1196-57-2Recommanded Product: 2-Quinoxalinol).
2-Quinoxalinol (cas: 1196-57-2) belongs to quinoxaline derivatives. Quinoxaline derivatives are important constituents of pharmacologically active compounds, including antibacterial, antibiotic and antineoplastic, antifungal, anti-inflammatory and analgesic drugs. Quinoxalines are used in the treatment of bacterial, cancer, and HIV infections. Moreover, varenicline, a clinical drug is used for treating nicotine addiction, also contains quinoxaline moiety.Recommanded Product: 2-Quinoxalinol
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider