Photo-Induced Cross-Dehydrogenative Alkylation of Heteroarenes with Alkanes under Aerobic Conditions was written by Xu, Jun;Cai, Heng;Shen, Jiabin;Shen, Chao;Wu, Jie;Zhang, Pengfei;Liu, Xiaogang. And the article was included in Journal of Organic Chemistry in 2021.Reference of 55687-34-8 This article mentions the following:
A Minisci-type cross-dehydrogenative alkylation in an aerobic atm. using abundant and inexpensive cerium chloride as a photocatalyst and air as an oxidant was reported. This photoreaction exhibited excellent tolerance to functional groups and was suitable for both heteroarene and alkane substrates under mild conditions, generating the corresponding products in moderate-to-good yields. This method provided an alternative approach for the late-stage functionalization of valuable substrates. In the experiment, the researchers used many compounds, for example, 6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8Reference of 55687-34-8).
6-Bromoquinoxalin-2(1H)-one (cas: 55687-34-8) belongs to quinoxaline derivatives. Quinoxalines are important class of heterocyclic compounds, associated with wider pharmacological applications. Quinoxalines are used in the treatment of bacterial, cancer, and HIV infections. Moreover, varenicline, a clinical drug is used for treating nicotine addiction, also contains quinoxaline moiety.Reference of 55687-34-8
Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider