Iijima, Chihoko et al. published their research in Yakugaku Zasshi in 1988 | CAS: 5424-05-5

Quinoxalin-2-amine (cas: 5424-05-5) belongs to quinoxaline derivatives. Quinoxalines have received a significant amount of attention due to their potential use in fighting various pathophysiological conditions like epilepsy, Parkinson’s, and Alzheimer’s diseases. Quinoxalines are used in the treatment of bacterial, cancer, and HIV infections. Moreover, varenicline, a clinical drug is used for treating nicotine addiction, also contains quinoxaline moiety.Category: quinoxaline

Quinoxalines. XXIII. Reaction of 2-chloroquinoxaline with nucleophiles was written by Iijima, Chihoko;Hayashi, Eisaku. And the article was included in Yakugaku Zasshi in 1988.Category: quinoxaline This article mentions the following:

2-Chloroquinoxaline (I, R = Cl) reacted with NaI, NaSO2C6H4R1-4 (R1 = H, Me), or KSCN to afford quinoxaline derivatives I (R = I, SO2C6H4R1-4, SCN; R1 = H, Me) in good yields. Cyano and nitro groups were introduced into the 2-position of quinoxaline in low yield by using KCN and AgNO. In the experiment, the researchers used many compounds, for example, Quinoxalin-2-amine (cas: 5424-05-5Category: quinoxaline).

Quinoxalin-2-amine (cas: 5424-05-5) belongs to quinoxaline derivatives. Quinoxalines have received a significant amount of attention due to their potential use in fighting various pathophysiological conditions like epilepsy, Parkinson’s, and Alzheimer’s diseases. Quinoxalines are used in the treatment of bacterial, cancer, and HIV infections. Moreover, varenicline, a clinical drug is used for treating nicotine addiction, also contains quinoxaline moiety.Category: quinoxaline

Referemce:
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N2 | ChemSpider