Synthetic Route of 2213-63-0, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 2213-63-0, molcular formula is C8H4Cl2N2, introducing its new discovery.
Electrophile-Induced Cyclization of 3-Alkynyl-2-arylquinoxalines: A Method for Benzo- and Naphthophenazine Synthesis
A facile synthesis of benzo[a]-, naphtho[1,2-a]- and naphtho[2,1-a]phenazines by ICl-promoted 6-endo-dig cyclization of 3-alkynyl-2-arylquinoxalines has been developed. The starting 3-alkynyl-2-arylquinoxalines were synthesized from 2,3-dichloroquinoxaline by two successive Sonogashira and Suzuki?Miyaura reactions. The method works well for 3-alkynyl-2-arylquinoxalines bearing various functional groups at the alkyne moiety. The arrangement and nature of the substituent in the 2-aryl fragment affect the regioselectivity of the cyclization. For the substrate of one particular type, namely 2-(4-methoxyphenyl)-3-(p-tolylethynyl)quinoxaline, the treatment with ICl leads to the alternative 5-endo-dig cyclization followed by demethylation of the methoxy group to give a spirocyclohexadienone derivative.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 2213-63-0 is helpful to your research. Synthetic Route of 2213-63-0
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Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1341 | ChemSpider