With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.14121-55-2,1,2,3,4-Tetrahydro-2,3-dioxoquinoxaline-6-carboxylic acid,as a common compound, the synthetic route is as follows.
Add 12 mmol of 2,3-dihydroxy-quinoxaline-6-carboxylic acid to a 150 ml three-necked flask,Add 30ml of dichloromethane and stir, heat to 40 C,Subsequently, 2 equivalents of thionyl chloride and 3 drops of N, N-dimethylformamide were added and the reaction was continued for 3-4 hours.Removal of the solvent gave 2,3-dichloro-quinoxaline-6-carbonyl chloride.
The synthetic route of 14121-55-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Northeast Agricultural University; Fu Ying; Ye Fei; Gao Shuang; Guo Keliang; (18 pag.)CN110835321; (2020); A;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider