2958-87-4, 2,3,6-Trichloroquinoxaline is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,2958-87-4
To a solution of 2,3,6-trichloro-quinoxaline (100 mg, 0.43 mmol) in DMF (3 mL) was added N-methylpiperazine (0.47 mL, 0.43 mmol). The reaction mixture was stirred for 12 h, and then the solvent was removed in vacuo. The residue was purified by silica gel chromatography to give 47 mg of 2,6-dichloro-3-(4-methyl-piperazin-1-yl)-quinoxaline and 28 mg of 3,6-dichloro-2-(4-methyl-piperazin-1-yl)-quinoxaline. 2,6-Dichloro-3-(4-methyl-piperazin-1-yl)-quinoxaline: 1H NMR (400 MHz, CDCl3): 7.80 (d, J=2.3 Hz, 1H), 7.77 (d, J=8.8 Hz, 1H), 7.46-7.43 (dd, J=8.8, 2.3 Hz, 2H), 3.63-3.62 (m, 4H), 2.64-2.61 (m, 4H), 2.38 (s, 3H). 3,6-Dichloro-2-(4-methyl-piperazin-1-yl)-quinoxaline: 1H NMR (400 MHz, CDCl3): 7.85 (d, J=2.3 Hz, 1H), 7.75 (d, J=8.8 Hz, 1H), 7.59-7.56 (dd, J=8.8, 2.3 Hz, 2H), 3.63-3.61 (m, 4H), 2.64-2.62 (m, 4H), 2.39 (s, 3H).
As the paragraph descriping shows that 2958-87-4 is playing an increasingly important role.
Reference£º
Patent; Edwards, James P.; Venable, Jennifer D.; US2005/70527; (2005); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider