Downstream synthetic route of 55687-02-0

The synthetic route of 55687-02-0 has been constantly updated, and we look forward to future research findings.

55687-02-0, 6-Bromo-2-chloroquinoxaline is a quinoxaline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

6-bromo, 2-chloroquinoxaline (0.25 g, 1.02 mmol) was dissolved in DMSO (8 mL) at room temperature and 4-fluoro benzyl amine (0.64 g, 5.1 mmol) was added. The reaction mixture was stirred at room temperature overnight. After completion of the reaction, the reaction mixture was poured onto ice water (100 mL) with stirring for 30 minutes. The precipitated product was filtered off and washed by water and dried in vacuo to afford the solid crude product.The product was purified by column chromatography using neutral silica gel of 60-120 mesh size. A gradient of 1-2% methanol in DCM was used to elute the title compound (0.35 g, 100%)., 55687-02-0

The synthetic route of 55687-02-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; SENTINEL ONCOLOGY LIMITED; BOYLE, Robert, George; WALKER, David, Winter; WO2010/136755; (2010); A1;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider