With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.32601-86-8,2-Chloro-3-methylquinoxaline,as a common compound, the synthetic route is as follows.
6.4 g of methyl p-hydroxybenzoate and 5.3 g of potassium carbonate were dissolved in 250 ml of N,N-dimethylformamide and reacted at 85 C for 12 h.Then, 7 g of 2-chloro-3-methylquinoxaline obtained in the step (2) was added thereto, and after continuing the reaction for 12 hours, 250 ml of water was added to the reaction solution.The aqueous phase was extracted twice with ethyl acetate.The crude product was purified by silica gel column chromatography (eluent: petroleum ether: ethyl acetate = 50:1, v: v)., 32601-86-8
As the paragraph descriping shows that 32601-86-8 is playing an increasingly important role.
Reference£º
Patent; Shandong University; Li Xun; Li Zhiyu; Liu Yuantao; Yuan Mingxia; Zhou Huaiyu; Zhou Jianfeng; Han Xuemei; (21 pag.)CN104529915; (2018); B;,
Quinoxaline – Wikipedia
Quinoxaline | C8H6N2 | ChemSpider