One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Application In Synthesis of 7-Bromo-1-methyl-1H-quinoxalin-2-one, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 82019-32-7, Name is 7-Bromo-1-methyl-1H-quinoxalin-2-one, molecular formula is C9H7BrN2O
Direct C?H Trifluoromethylation of Quinoxalin-2(1H)-ones under Transition-Metal-Free Conditions
Disclosed herein is a direct C?H trifluoromethylation of quinoxalin-2(1H)-ones with sodium trifluoromethanesulfinate. This protocol affords a series of 3-trifluoromethylquinoxalin-2(1H)-one derivatives in moderate to excellent yields under transition-metal-free conditions. The present methodology features utilization of the inexpensive trifluoromethyl source without transition-metal-catalysts, mild reaction conditions and high functional group tolerance, which promises a convenient and efficient access to pharmaceutically interesting quinoxalinones. (Figure presented.).
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Application In Synthesis of 7-Bromo-1-methyl-1H-quinoxalin-2-one, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 82019-32-7, in my other articles.
Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1928 | ChemSpider