One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, HPLC of Formula: C9H7BrN2O, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 82019-32-7, Name is 7-Bromo-1-methyl-1H-quinoxalin-2-one, molecular formula is C9H7BrN2O
Direct C?H difluoromethylation of heterocycles via organic photoredox catalysis
The discovery of modern medicine relies on the sustainable development of synthetic methodologies to meet the needs associated with drug molecular design. Heterocycles containing difluoromethyl groups are an emerging but scarcely investigated class of organofluoro molecules with potential applications in pharmaceutical, agricultural and material science. Herein, we developed an organophotocatalytic direct difluoromethylation of heterocycles using O2 as a green oxidant. The C?H oxidative difluoromethylation obviates the need for pre-functionalization of the substrates, metals and additives. The operationally straightforward method enriches the efficient synthesis of many difluoromethylated heterocycles in moderate to excellent yields. The direct difluoromethylation of pharmaceutical moleculars demonstrates the practicability of this methodology to late-stage drug development. Moreover, 2?-deoxy-5-difluoromethyluridine (F2TDR) exhibits promising activity against some cancer cell lines, indicating that the difluoromethylation methodology might provide assistance for drug discovery.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. HPLC of Formula: C9H7BrN2O, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 82019-32-7, in my other articles.
Reference：
Quinoxaline – Wikipedia,
Quinoxaline | C8H6N1941 | ChemSpider